Table 2. Inter-examination Precision for Hepatic PDFF Estimation.
Inter-examination ICC [95% CI] | Inter-examination SD | Inter-examination Range (Minimum-Maximum) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
3-Echo | 4-Echo | 5-Echo | 6-Echo | 3-Echo | 4-Echo | 5-Echo | 6-Echo | 3-Echo | 4-Echo | 5-Echo | 6-Echo | |
Segment | ||||||||||||
1 | 0.995 [0.991,0.997] | 0.995 [0.991,0.998] | 0.995 [0.991,0.998] | 0.995 [0.991,0.998] | 0.54 | 0.54 | 0.54 | 0.54 | 1.03 (11.38-12.41) | 1.03 (11.29-12.32) | 1.02 (11.35-12.37) | 1.03 (11.28-12.31) |
2 | 0.992 [0.985,0.996] | 0.992 [0.985,0.996] | 0.992 [0.985,0.996] | 0.992 [0.985,0.996] | 0.55 | 0.56 | 0.58 | 0.59 | 1.05 (9.08-10.13) | 1.07 (8.93-10.00) | 1.11 (9.00-10.11) | 1.12 (8.88-10.00) |
3 | 0.994 [0.989,0.997] | 0.994 [0.988,0.997] | 0.993 [0.987,0.996] | 0.993 [0.987,0.996] | 0.55 | 0.55 | 0.62 | 0.61 | 1.05 (10.34-11.39) | 1.04 (10.23-11.27) | 1.16 (10.21-11.37) | 1.16 (10.11-11.27) |
4a | 0.995 [0.992,0.998] | 0.996 [0.992,0.998] | 0.996 [0.992,0.998] | 0.996 [0.992,0.998] | 0.47 | 0.46 | 0.46 | 0.46 | 0.88 (10.48-11.36) | 0.87 (10.36-11.23) | 0.85 (10.55-11.40) | 0.87 (10.41-11.28) |
4b | 0.995 [0.992,0.998] | 0.995 [0.992,0.998] | 0.996 [0.992,0.998] | 0.996 [0.993,0.998] | 0.45 | 0.46 | 0.46 | 0.44 | 0.86 (11.08-11.94) | 0.88 (10.95-11.83) | 0.88 (11.07-11.95) | 0.84 (11.00-11.84) |
5 | 0.997 [0.994,0.998] | 0.997 [0.994,0.998] | 0.997 [0.994,0.998] | 0.997 [0.994,0.998] | 0.42 | 0.42 | 0.42 | 0.43 | 0.79 (11.12-11.91) | 0.8 (10.98-11.78) | 0.79 (11.00-11.79) | 0.81 (10.88-11.69) |
6 | 0.997 [0.995,0.999] | 0.997 [0.995,0.999] | 0.998 [0.996,0.999] | 0.998 [0.996,0.999] | 0.39 | 0.39 | 0.36 | 0.37 | 0.74 (11.82-12.56) | 0.74 (11.72-12.46) | 0.69 (11.85-12.54) | 0.69 (11.77-12.46) |
7 | 0.995 [0.991,0.998] | 0.995 [0.991,0.997] | 0.996 [0.993,0.998] | 0.996 [0.992,0.998] | 0.50 | 0.49 | 0.45 | 0.46 | 0.96 (12.36-13.32) | 0.93 (12.28-13.21) | 0.85 (12.39-13.24) | 0.87 (12.32-13.19) |
8 | 0.992 [0.985,0.996] | 0.992 [0.986,0.996] | 0.993 [0.986,0.996] | 0.993 [0.987,0.996] | 0.66 | 0.65 | 0.62 | 0.61 | 1.24 (11.60-12.84) | 1.23 (11.47-12.70) | 1.16 (11.60-12.76) | 1.14 (11.49-12.63) |
Lobe | ||||||||||||
Left | 0.998 [0.997,0.999] | 0.998 [0.997,0.999] | 0.998 [0.996,0.999] | 0.998 [0.996,0.999] | 0.30 | 0.31 | 0.34 | 0.33 | 0.57 (10.68-11.25) | 0.58 (10.57-11.14) | 0.64 (10.63-11.27) | 0.63 (10.53-11.16) |
Right | 0.999 [0.998,0.999] | 0.999 [0.998,0.999] | 0.999 [0.998,0.999] | 0.999 [0.998,1.00] | 0.27 | 0.27 | 0.25 | 0.26 | 0.52 (11.93-12.44) | 0.52 (11.81-12.33) | 0.48 (11.91-12.39) | 0.48 (11.81-12.30) |
Whole liver | 0.999 [0.998,1.00] | 0.999 [0.998,1.00] | 0.999 [0.998,1.00] | 0.999 [0.998,1.00] | 0.23 | 0.23 | 0.24 | 0.24 | 0.44 (11.29-11.73) | 0.44 (11.18-11.62) | 0.45 (11.26-11.71) | 0.45 (11.17-11.62) |
Note – Table shows inter-examination intra-class correlation coefficient (ICC), standard deviation (SD), and range for three-, four-, five-, and six-echo reconstruction methods at the segmental, lobar, and whole liver anatomic levels. For ICC values, the 95% confidence intervals are shown in brackets. For ranges, the corresponding minimum and maximum values that span the range are shown in parentheses. SD and range (and the corresponding minimum and maximum values) are averages of the 29 subjects' individual inter-examinations SDs and ranges (and corresponding minimum and maximum values). Units for SD and range are percentage points. CI = Confidence Interval