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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Magn Reson Imaging. 2013 Oct 17;39(5):1265–1271. doi: 10.1002/jmri.24284

Table 2. Inter-examination Precision for Hepatic PDFF Estimation.

Inter-examination ICC [95% CI] Inter-examination SD Inter-examination Range (Minimum-Maximum)
3-Echo 4-Echo 5-Echo 6-Echo 3-Echo 4-Echo 5-Echo 6-Echo 3-Echo 4-Echo 5-Echo 6-Echo
Segment
1 0.995 [0.991,0.997] 0.995 [0.991,0.998] 0.995 [0.991,0.998] 0.995 [0.991,0.998] 0.54 0.54 0.54 0.54 1.03 (11.38-12.41) 1.03 (11.29-12.32) 1.02 (11.35-12.37) 1.03 (11.28-12.31)
2 0.992 [0.985,0.996] 0.992 [0.985,0.996] 0.992 [0.985,0.996] 0.992 [0.985,0.996] 0.55 0.56 0.58 0.59 1.05 (9.08-10.13) 1.07 (8.93-10.00) 1.11 (9.00-10.11) 1.12 (8.88-10.00)
3 0.994 [0.989,0.997] 0.994 [0.988,0.997] 0.993 [0.987,0.996] 0.993 [0.987,0.996] 0.55 0.55 0.62 0.61 1.05 (10.34-11.39) 1.04 (10.23-11.27) 1.16 (10.21-11.37) 1.16 (10.11-11.27)
4a 0.995 [0.992,0.998] 0.996 [0.992,0.998] 0.996 [0.992,0.998] 0.996 [0.992,0.998] 0.47 0.46 0.46 0.46 0.88 (10.48-11.36) 0.87 (10.36-11.23) 0.85 (10.55-11.40) 0.87 (10.41-11.28)
4b 0.995 [0.992,0.998] 0.995 [0.992,0.998] 0.996 [0.992,0.998] 0.996 [0.993,0.998] 0.45 0.46 0.46 0.44 0.86 (11.08-11.94) 0.88 (10.95-11.83) 0.88 (11.07-11.95) 0.84 (11.00-11.84)
5 0.997 [0.994,0.998] 0.997 [0.994,0.998] 0.997 [0.994,0.998] 0.997 [0.994,0.998] 0.42 0.42 0.42 0.43 0.79 (11.12-11.91) 0.8 (10.98-11.78) 0.79 (11.00-11.79) 0.81 (10.88-11.69)
6 0.997 [0.995,0.999] 0.997 [0.995,0.999] 0.998 [0.996,0.999] 0.998 [0.996,0.999] 0.39 0.39 0.36 0.37 0.74 (11.82-12.56) 0.74 (11.72-12.46) 0.69 (11.85-12.54) 0.69 (11.77-12.46)
7 0.995 [0.991,0.998] 0.995 [0.991,0.997] 0.996 [0.993,0.998] 0.996 [0.992,0.998] 0.50 0.49 0.45 0.46 0.96 (12.36-13.32) 0.93 (12.28-13.21) 0.85 (12.39-13.24) 0.87 (12.32-13.19)
8 0.992 [0.985,0.996] 0.992 [0.986,0.996] 0.993 [0.986,0.996] 0.993 [0.987,0.996] 0.66 0.65 0.62 0.61 1.24 (11.60-12.84) 1.23 (11.47-12.70) 1.16 (11.60-12.76) 1.14 (11.49-12.63)
Lobe
Left 0.998 [0.997,0.999] 0.998 [0.997,0.999] 0.998 [0.996,0.999] 0.998 [0.996,0.999] 0.30 0.31 0.34 0.33 0.57 (10.68-11.25) 0.58 (10.57-11.14) 0.64 (10.63-11.27) 0.63 (10.53-11.16)
Right 0.999 [0.998,0.999] 0.999 [0.998,0.999] 0.999 [0.998,0.999] 0.999 [0.998,1.00] 0.27 0.27 0.25 0.26 0.52 (11.93-12.44) 0.52 (11.81-12.33) 0.48 (11.91-12.39) 0.48 (11.81-12.30)
Whole liver 0.999 [0.998,1.00] 0.999 [0.998,1.00] 0.999 [0.998,1.00] 0.999 [0.998,1.00] 0.23 0.23 0.24 0.24 0.44 (11.29-11.73) 0.44 (11.18-11.62) 0.45 (11.26-11.71) 0.45 (11.17-11.62)

Note – Table shows inter-examination intra-class correlation coefficient (ICC), standard deviation (SD), and range for three-, four-, five-, and six-echo reconstruction methods at the segmental, lobar, and whole liver anatomic levels. For ICC values, the 95% confidence intervals are shown in brackets. For ranges, the corresponding minimum and maximum values that span the range are shown in parentheses. SD and range (and the corresponding minimum and maximum values) are averages of the 29 subjects' individual inter-examinations SDs and ranges (and corresponding minimum and maximum values). Units for SD and range are percentage points. CI = Confidence Interval