Table 5.
Estimates of Explained Phenotypic Variance (h2SNP) Attributable to GABA System SNPs and All Available SNPs, Separately for Autosomal and Chromosome X Markers
| Drinking Index | Alcohol Abuse and Dependence Symptoms |
|||
|---|---|---|---|---|
| h2SNP | (SE) | h2SNP | (SE) | |
| All Autosomal SNPs | 0.156* | (.100) | 0.09 | (.100) |
| GABA Autosomal SNPs | 0 | (.006) | 0 | (.006) |
| All Chr. X SNPs | 0 | (.016) | 0.001 | (.016) |
| GABA Chr. X SNPs | 0 | (.001) | 0 | (.001) |
Likelihood ratio test p < .05
Analyzed N = 3614 for the drinking index and analyzed N = 3621 for alcohol abuse and dependence symptoms