Effect of treatment on forearm blood flow (FBF) response to intra-arterial bradykinin, with and without intra-arterial enalaprilat, and to substance P, with and without intra-arterial enalaprilat (n=12). Data presented as mean ± standard error of the mean. Quadratic model-based p-values presented in the text. *p<0.05 versus placebo at same peptide dose, †p<0.05 versus dipeptidyl peptidase-4 inhibition (DPP4i) at same peptide dose, ACEi indicates angiotensin-converting enzyme inhibition.