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. Author manuscript; available in PMC: 2014 Sep 24.
Published in final edited form as: Nat Commun. 2014 Mar 24;5:3483. doi: 10.1038/ncomms4483

Figure 6. The UPRmt is not required for isp-1(qm150) longevity.

Figure 6

(a) Knockdown of atfs-1 does not attenuate the longevity of complex III mutant isp-1(qm150). N2 fed EV(RNAi) (mean 19.7 ± .2, n = 365), N2 fed atfs-1(RNAi) (mean 20 ± .2 days, n = 346, p = 0.399), isp1(qm150) fed EV(RNAi) (mean 28.2 ± .6 days, n = 206), isp-1(qm150) fed atfs-1(RNAi) (mean 28.3 ± .5 days, n = 293, p = 0.612). (b) hsp-6p::gfp induction by isp-1(qm150) mutation is attenuated by atfs-1(RNAi). Scale bar, 0.3 mm. Lifespan experiments in this figure represent pooled data, are indicated as mean +/− SEM, and p-values were calculated using Wilcoxon rank-sum test. Data by individual experiment and statistical analysis provided in Supplementary Materials (Supplementary Data 2).