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. 2014 Mar 27;7:27. doi: 10.1186/1756-8722-7-27

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Copyright © 2014 Araten et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Time course of hematological parameters of patient 4 in relation to eculizumab treatment and SSAE treatment. Eculizumab was started in December 2007. SSAE of the three main branches of the splenic artery was performed in June, July, and November 2008. It is seen that the rather severe thrombocytopenia did not respond to eculizumab (nor was that expected), but it did respond to SSAE; the transfusion requirement decreased somewhat on eculizumab but much more after SSAE.