Table 4.

Multivariate Cox regression analysis of factors associated with BCSS and DFI for ER-positive cases in the unselected series

Variable	BCSS		DFI
	Hazard ratio (95 % CI)	p value	Hazard ratio (95 % CI)	p value
Tumour size (cm)	0.48 (0.28–0.85)	0.011	0.57 (0.38–0.85)	0.007
Tumour stage	1.69 (1.33–2.16)	<0.001	1.61 (1.30–1.99)	<0.001
Tumour grade	1.77 (1.37–2.30)	<0.001	1.22 (0.99–1.49)	0.059
HER2/HER3 heterodimer	0.46 (0.29–0.74)	0.001	0.67 (0.43–1.06)	0.087