Table 1.
Association between SLC38A1 expression and clinicopathological factors of GC patients
|
Clinicopathological variables |
Total |
SLC38A1 positive expression |
|
|---|---|---|---|
| n | n | P | |
| Age |
|
|
0.007 |
| ≤ 60 years |
447 |
227 |
|
| > 60 years |
449 |
268 |
|
| Sex |
|
|
0.437 |
| Male |
634 |
345 |
|
| Female |
262 |
150 |
|
| Location |
|
|
0.277 |
| Cardia |
144 |
86 |
|
| Corpus |
281 |
150 |
|
| Antrum |
440 |
246 |
|
| Whole |
31 |
13 |
|
| Operation manner |
|
|
0.590 |
| Subtotal gastrectomy |
400 |
217 |
|
| Total gastrectomy |
496 |
278 |
|
| Size (Diameter) |
|
|
0.321 |
| ≤ 6 cm |
706 |
384 |
|
| > 6 cm |
190 |
111 |
|
| Differentiation |
|
|
<0.001 |
| High/moderate |
553 |
337 |
|
| Low/undifferentiated |
343 |
158 |
|
| Gastric wall invasion |
|
|
0.151 |
| T1/T2 |
308 |
160 |
|
| T3/T4 |
588 |
335 |
|
| lymph node metastasis |
|
|
0.026 |
| Negative |
346 |
175 |
|
| Positive |
550 |
320 |
|
| TNM stage |
|
|
0.001 |
| I/II |
427 |
212 |
|
| III |
469 |
283 |
|
| Lymphovascular invasion |
|
|
0.275 |
| Negative |
850 |
466 |
|
| Positive |
46 |
29 |
|
| p53 expression |
|
|
0.382 |
| Negative |
401 |
228 |
|
| Positive |
495 |
267 |
|
| PCNA expression |
|
|
0.012 |
| Negative |
99 |
43 |
|
| Positive | 797 | 452 | |