Table 2.
Univariate and multivariate analysis of the prognostic significance of individual clinicopathological factors on survival
| |
Univariate analysis |
Multivariate analysis |
||||||
|---|---|---|---|---|---|---|---|---|
|
HR |
95.0% CI |
P value |
HR |
95.0% CI |
P value |
|||
| Lower | Upper | Lower | Upper | |||||
| Size (≤ 6 cm vs. > 6 cm) |
1.816 |
1.429 |
2.309 |
.000 |
1.327 |
1.039 |
1.696 |
.024 |
| TNM (I/II vs. III) |
4.214 |
3.292 |
5.393 |
.000 |
3.416 |
2.637 |
4.424 |
.000 |
| Differentiation (high/moderate vs. low/undifferentiated) |
1.876 |
1.509 |
2.332 |
.000 |
1.565 |
1.249 |
1.960 |
.000 |
| Nerve invasion (negative vs. positive) |
2.070 |
1.421 |
3.015 |
.000 |
1.353 |
.910 |
2.011 |
.135 |
| Lymphovascular invasion (negative vs. positive) |
2.664 |
1.770 |
4.011 |
.000 |
1.931 |
1.258 |
2.964 |
.003 |
| PCNA (negative vs. positive) |
1.794 |
1.174 |
2.742 |
0.007 |
1.695 |
1.098 |
2.617 |
.017 |
| P53 (negative vs. positive) |
1.277 |
1.024 |
1.593 |
0.03 |
1.046 |
.835 |
1.310 |
.695 |
| SLC38A1 (negative vs. positive) | 1.191 | 1.065 | 1.332 | 0.002 | 1.122 | 1.001 | 1.258 | .041 |