Table 2.

Brain regions demonstrating differential BOLD responses during individually tailored symptom provocation in OCD.

		Coordinates
Brain regionsa	Side	Brodmann areaa	x	y	z		Volume, mm3	F valueb
Group-by-picture type interaction
Subcortical
Thalamus	L		−14	−11	14		1198	10.46
Caudate nucleus/body	L		−15	−11	18		193*	7.93
Subthalamic nucleus	L		−7	−11	−6		274	17.93
Lentiform/globus pallidus	L		−19	−12	−6		260	14.58
Amygdala	R		26	−2	−12		558	8.81
	L		−28	−8	−12		937	9.01
Frontal lobes
Orbitofrontal cortex	R	47	35	31	−6		162*	7.75
Ventrolateral prefrontal cortex	R	10	26	58	3		517	10.83
Anterior insula	R	13	44	7	12		276	9.43
Temporal lobes
Parahippocampal gyrus	R	36	35	−29	−21		1182	15.81
	L	27	−22	−32	−1		984	9.11
Middle temporal gyrus	L	19	−37	−80	21		710	9.68
Occipital lobes
Posterior cingulate cortex/precuneus	R	31	11	−53	27		317	7.99
Cuneus	R	7	11	−68	33		540	9.83
	L	18	−4	−92	21		287	7.94
Group-by-picture type-by-strategy interaction
Subcortical
Amygdala	L		−28	−5	−11		108	6.42
Anterior cerebellum	R		8	−56	0		334	9.56
Frontal lobes
Dorsal anterior cingulate cortex	L	24, 31	−10	−11	45		362	7.65
Parietal lobes
Insulo-opercular region	L	13, 40	−55	−32	18		455	9.88

^aAccording to the Talairach Daemon atlas (http://www.nitrc.org/projects/tal-daemon/).

^bAll activations are effects observed in whole-brain analyses significant at p < 0.005 corrected for multiple comparisons p (cor)clusterwise < 0.05

^*Significant at p < 0.005 uncorrected.