Table 2. Significantly Associated SNPs (P < 0.05) With Sustained Virological Response to Interferon and Ribavirin Therapy a.
SNPs | MAF | Responder MAF (n = 47) | Non-Responder MAF (n = 28) | OR (95% CI) | P Value |
---|---|---|---|---|---|
RS8109886 | 0.41 | 0.32 | 0.44 | 3.6 (1.9-6.5) | 0.0001 |
RS8113007 | 0.25 | 0.19 | 0.33 | 3.6 (1.9-6.5) | 0.0001 |
RS12979860 | 0.3 | 0.23 | 0.41 | 3.1 (1.7-5.3) | 0.0002 |
RS11665818 | 0.38 | 0.29 | 0.5 | 2.9 (1.6-5.3) | 0.0003 |
RS955155 | 0.33 | 0.26 | 0.38 | 2.9 (1.6-5.1) | 0.0004 |
RS688187 | 0.31 | 0.27 | 0.38 | 2.7( 1.5-4.7) | 0.0011 |
RS4803217 | 0.3 | 0.25 | 0.38 | 2.7 (1.5-4.7) | 0.0011 |
RS8105790 | 0.19 | 0.16 | 0.25 | 2.6 (1.4-4.6) | 0.0022 |
RS4803221 | 0.22 | 0.16 | 0.27 | 2.6 (1.4-4.6) | 0.0022 |
RS8099917 | 0.19 | 0.16 | 0.25 | 2.6 (1.4-4.6) | 0.0022 |
RS7248668 | 0.19 | 0.16 | 0.25 | 2.6(1.4-4.6) | 0.0022 |
RS12972991 | 0.22 | 0.17 | 0.3 | 2.5(1.4-4.5) | 0.0024 |
RS11671087 | 0.41 | 0.32 | 0.5 | 2.2 (1.2-3.9) | 0.0130 |
a Abbreviations: CI, confidence interval; MAF, minor allele frequency; OR: odds ratio.