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. Author manuscript; available in PMC: 2014 Apr 12.
Published in final edited form as: Cancer Cell. 2012 Dec 11;22(6):812–824. doi: 10.1016/j.ccr.2012.11.003

Figure 6. MI-2 Is Nontoxic to Animals.

Figure 6

(A) Dose scheme for toxicity 1 (increasing daily dose) and toxicity 2 (same daily dose) experiments show daily and cumulative doses for each experiment.

(B) The y axis depicts mean ± SEM body weight of animals studied in both the incremental and cumulative dose schemes. Toxicity 1, p = 0.59 t test; toxicity 2, p = 0.52 t test.

(C) H&E staining for the indicated tissues in animals treated with vehicle, MI-2 25 mg/kg daily for 14 days, or MI-2 25 mg/kg daily for 14 days followed by a 10 day washout.

See also Table S2.