Table 2.
Sample Sizes, Group Means, and Standard Deviations for the SPEM, PPI, and Auditory ERP Outcomes in the Schizophrenia and Psychotic Bipolar I Disorder Probands, Their Relatives, and Healthy Controls
| SZP | BDP | SZR | BDR | HC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Measures | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) |
| SPEM (gain) | ||||||||||
| MPG_9.9 | 57 | 0.86 (0.10) | 39 | 0.85 (0.13) | 29 | 0.88 (0.10) | 24 | 0.89 (0.10) | 39 | 0.91 (0.08) |
| MPG_18.7 | 57 | 0.82 (0.12) | 39 | 0.79 (0.16) | 29 | 0.84 (0.12) | 23 | 0.85 (0.12) | 39 | 0.86 (0.11) |
| MPG_25.0 | 57 | 0.73 (0.16) | 39 | 0.71 (0.17) | 29 | 0.77 (0.11) | 24 | 0.76 (0.17) | 39 | 0.81 (0.13) |
| PPG_9.9 | 57 | 0.66 (0.10) | 39 | 0.65 (0.12) | 29 | 0.69 (0.09) | 24 | 0.68 (0.10) | 39 | 0.73 (0.10) |
| PPG_18.7 | 57 | 0.52 (0.13) | 39 | 0.52 (0.11) | 29 | 0.55 (0.11) | 24 | 0.57 (0.13) | 39 | 0.62 (0.11) |
| PPG_25.0 | 55 | 0.48 (0.13) | 38 | 0.46 (0.16) | 29 | 0.48 (0.12) | 24 | 0.48 (0.13) | 38 | 0.57 (0.14) |
| PPI and PPF (Δ%) | ||||||||||
| PPI | 34 | 43.58 (34.41) | 26 | 46.82 (29.48) | 24 | 55.16 (24.53) | 21 | 68.98 (18.95) | 22 | 49.93 (20.61) |
| PPF | 34 | −10.9 (34.57) | 26 | −6.39 (35.79) | 23 | −2.11 (36.81) | 21 | −17.41 (41.44) | 22 | −9.52 (48.08) |
| Auditory ERP (dB) | ||||||||||
| Beta | 40 | −0.62 (5.34) | 33 | −1.04 (6.07) | 26 | 0.93 (6.58) | 22 | 0.85 (4.95) | 13 | 4.03 (4.58) |
| Theta/alpha | 40 | 8.85 (6.11) | 33 | 9.47 (6.02) | 26 | 9.75 (5.91) | 22 | 9.99 (7.73) | 13 | 14.63 (6.47) |
Note: SPEM, smooth pursuit eye movement; ERP, event-related potentials; HC, healthy controls; MPG, maintenance pursuit gain (at 9.9°/s, 18.7°/s, and 25.0°/s velocity); PPG, predicative pursuit gain (at 9.9°/s, 18.7°/s, and 25.0°/s velocity); PPI, prepulse inhibition at 120 ms interstimulus interval; PPF, prepulse facilitation at 4500 ms interstimulus interval; beta, ERP beta frequency score; theta/alpha, ERP theta/alpha frequency score.