Table 2.
Phenotype | Chromosome Where Marker Is Located | Nearest Gene | OR |
---|---|---|---|
Schizophrenia | 1 | MIR137 | 1.12 |
2 | VRK2 | 1.09 | |
2 | ZNF804A | 1.10 | |
2 | PCGEM1 | 1.20 | |
6 | MHC | 1.22 | |
8 | MMP16 | 1.10 | |
8 | CSMD1 | 1.11 | |
8 | LSM1 | 1.19 | |
10 | CNNM2 | 1.10 | |
10 | NT5C2 | 1.15 | |
11 | AMBRA1 | 1.25 | |
11 | NRGN | 1.12 | |
18 | CCDC68 | 1.09 | |
18 | TCF4 | 1.20 | |
Bipolar disorder | 11 | ODZ4 | 1.14 |
12 | CACNA1C | 1.14 | |
19 | NCAN | 1.17 | |
Schizophrenia and bipolar disorder combined | 2 | ZNF804A | 1.11 |
3 | ITIH3-ITIH4 | 1.12 | |
10 | ANK3 | 1.22 | |
12 | CACNA1C | 1.11 |
Notes: Based on studies with large samples (minimum of around 10 000 cases and 10 000 controls) and SNP markers showing associations at genome-wide level of statistical significance (P < 5 × 10−8). Reprinted from Sullivan et al 70 , Copyright (2012), with permission from Macmillan Publishers Ltd.