Table 3. TTR amyloid deposition is associated with more LV fibrosis and lower heart weight after adjustment for age and presence of HFpEF.
Regression coefficient | SE | p value | |
---|---|---|---|
Percent Fibrosis (WFDM) | |||
Age at death (per 10 yrs) | 0.5% | 0.3% | 0.09 |
HFpEF (vs Control) | 2.1% | 0.4% | <0.001 |
wtTTR present (vs absent) | 2.0% | 0.7% | 0.005 |
Percent Expected Heart Weight | |||
HFpEF (vs Control) | 32.2% | 2.5% | <0.001 |
wtTTR present (vs absent) | −8.2% | 4.0% | 0.04 |
Abbreviations: SE, standard error; WFDM, whole-field digital microscopy