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. 2014 Feb 3;16(5):728–734. doi: 10.1093/neuonc/not319

Fig. 1.

Fig. 1.

Image registration, lesion extraction, and frequency map reconstruction. (A) Gadolinium-enhanced T1-weighted images are registered onto a standard averaged MRI (MNI152) using a normalized mutual information algorithm. Gd-enhanced lesions are extracted and assigned a value of “1” to voxels within the lesion and “0” to voxels not within the lesion. (B) Binary data containing the locations of Gd-enhanced lesions are summed, and a lesion frequency map is reconstructed.