Table 1. Influence of pH on intracellular CQ and Lys-01 concentration.

	pH 7.4	pH 6.8
CQ	34 ± 6 μM	5 ± 1 μM
Lys-01	89 ± 15 μM	52 ± 4 μM

HCT116 cells were exposed for 4 h to CQ (50 μM) or Lys-01 (50 μM) in medium buffered at pH 7.4 and 6.8. Whole cell lysate was subjected to HPLC analysis. Data are expressed as means ± standard deviations.