Table 1. Lipid profiles of apoE2-KI mice treated with FF or GFT505.

ApoE2-KI mice on a western-diet were treated by oral gavage with FF (200mpk) or GFT505 (10mpk) or vehicle for 14d (n=6 mice/group).

	Vehicle	FF	GFT505
TG (mg/dL)	278 ± 76	156 ±62*	110 ±50*
Total cholesterol (mg/dL)	1006 ± 190	459 ± 201**	384 ± 142***
HDL-cholesterol (mg/dL)	26 ± 7	62 ± 11***	71 ± 10***,#
non HDL-cholesterol (mg/dL)	980 ± 196	397 ± 203**	312 ± 142***

Values are expressed as means ± SEM. ANOVA;

^*P<.05;

^**P<.01;

^***P<.001 vs untreated mice;

^#P<.05 vs FF-treated mice.