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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Addiction. 2014 Feb 18;109(5):814–822. doi: 10.1111/add.12478

Table 3.

Association between rs4952 and nicotine dependence, conditioned on rs13273442 (Fixed effects meta-analysis model)

Nicotine (Fixed Effects) Het p
Ancestry Study N OR (CI) p
EA COGEND 1899 0.82 (0.56–1.21) 0.32
EA COGA 974 0.44 (0.22–0.86) 0.02
EA FSCD 558 1.39 (0.47–4.12) 0.55
EA Meta-analysis 3431 0.75 (0.54–1.03) 0.08 0.15
AA COGEND 676 0.43 (0.16–1.17) 0.10
AA COGA 373 1.38 (0.19–10.14) 0.75
AA FSCD 612 1.81 (0.19–17.19) 0.61
AA Meta-analysis 1661 0.59 (0.28–1.17) 0.13 0.33
EA+AA Meta-analysis 5092 0.72 (0.53–0.96) 0.02 0.26

Het p = p-value for a test of heterogeneity among the meta-analysis strata

Model: nicotine dependence = rs4952 + rs13273442 + sex + age quartile + alcohol dependence + cocaine dependence + marijuana dependence