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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Pharm Res. 2015 Mar;32(3):769–778. doi: 10.1007/s11095-013-1219-9

Figure 5. Knockdown of DGCR8 attenuates cellular survival pathways.

Figure 5

A. Tumors were continuously grown in mice injected with control cells whereas tumor significantly were reduced in mice injected with DGCR8KD cells(n=4,**p<0.01). B. DGCR8, phospho and total AKT, phospho and totalERK1/2 and GAPDH expression in DGCR8KD and control SKOV3 cells were detected by Western blot. Protein bands were quantified by densitometry (**p<0.01, ***p<0.001).