Table 1.
Clinical characteristics of 9 genetically confirmed HLRCC patients with renal tumors
| Pt | Sex | Age | Symptoms | Leiomyoma | Family Hx at Presentation | Kidney Mass | Size (cm) | pT | Metastasis | Follow-Up (Month) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 37 | Flank pain | Uterine at 32 | None | L /solitary | 4.9 | pT3a | RPLNs | DOD (44) |
| 2 | M | 38 | Flank pain, hematuria | None | None | R/solitary | 12.5 | pT3a | RPLNs, adrenal, liver, lung, bone | DOD (28) |
| 3 | F | 32 | Abdominal discomfort | Uterine (imaging only) | N/A (adopted) | R/ solitary | 9.2 | pT3a | RPLNs, lung, liver | DOD (23) |
| 4 | M | 24 | Flank pain | None | Mother ovarian ca | L /solitary | 5 | pT3a | RPLNs, lung | AWD (10) |
| 5 | M | 61 | Flank pain, hematuria | None | Father RCC, mother breast ca, daughter fibroid | L /two masses | 15; 3 | pT3a | RPLNs, adrenal, liver | DOD (8) |
| 6 | M | 42 | Flank pain, hematuria | None | None | L /solitary | 6.5 | pT3a | RPLNs, adrenal, liver | DOD (8) |
| 7 | M | 34 | Incidental renal mass | None | Father non-small cell lung ca | L /solitary | 12.2 | pT3a | RPLNs | AWD (10) |
| 8 | F | 30 | Flank pain | None | None | R /solitary | 6.7 | pT3a | RPLNs, adrenal | AWD (12) |
| 9 | F | 25 | Flank pain | Yes (but not identified initially) | Mother RCC | R/solitary | 11.5 | pT3a | RPLNs | NED (6) |
RPLNs: retroperitoneal lymph nodes; DOD: death of disease; AWD: alive with disease; RCC: renal cell carcinoma; ca:cancer