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. 2014 Apr 4;15:47. doi: 10.1186/1471-2202-15-47

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Copyright © 2014 RamaRao et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Calpain expression after soman and antidotes treatment. Efficacy of HI-6, atropine and midazolam on soman induced calpain protein levels of rats sacrificed at 30 min, 2.5 h, 1d and 7d time points (n = 4 per each time point). Calpain immunoreactivity levels in the rat hippocampus (A), cerebral cortex (B) and cerebellum (C) after soman poisoning (E- bar graph). Calpain levels in the rat hippocampus (F), cerebral cortex (G) and cerebellum (H) after antidotes treatment (J-bar graph). β-actin (D and I), was used as protein loading control. A difference of p < 0.05 was considered significant (*).