Table 3.
Mean values (± standard deviation) of biochemical variables in donkeys (n = 10) injected with digoxin
Time | Glucose (mmol/L) | CA (mmol/L) | BUN (mmol/L) | CRE (μmol/L) | AST (U/L) | CK (U/L) | GGT (U/L) | TBIL (μmol/L) | TP (g/L) | ALB (g/L) | GLOB (g/L) |
---|---|---|---|---|---|---|---|---|---|---|---|
T0 |
3.8 ± 0.6 |
3.0 ± 0.1 |
6.1 ± 0.6 |
44 ± 8 |
618 ± 157 |
1339 ± 1275 |
56 ± 10 |
2.2 ± 0.3 |
73.5 ± 7.2 |
35.9 ± 4.4 |
37.6 ± 11.1 |
T1 |
4.6 ± 0.9b |
2.9 ± 0.1 |
6.1 ± 0.4 |
44 ± 9 |
632 ± 137 |
1356 ± 1280 |
58 ± 14 |
2.5 ± 0.4 |
75.0 ± 5.6 |
45.4 ± 14.2 |
36.2 ± 11.2 |
T2 |
5.1 ± 0.8b |
3.0 ± 0.1 |
6.2 ± 0.4 |
42 ± 12 |
627 ± 136 |
1326 ± 1204 |
55 ± 8 |
2.5 ± 0.4 |
74.4 ± 4.3 |
37.9 ± 5.8 |
36.6 ± 9.7 |
T3 |
5.2 ± 0.8b |
3.0 ± 0.2 |
6.2 ± 0.5 |
44 ± 13 |
644 ± 114 |
1219 ± 1117 |
49 ± 12 |
2.8 ± 0.8 |
74.0 ± 3.7 |
37.8 ± 5.9 |
36.1 ± 9.0 |
T4 |
6.2 ± 1.1b |
2.9 ± 0.3 |
6.2 ± 0.4 |
43 ± 13 |
791 ± 226 |
1232 ± 1102 |
52 ± 11 |
2.5 ± 0.4 |
74.6 ± 4.6 |
36.9 ± 4.2 |
38.1 ± 8.0 |
T5 |
5.3 ± 0.9b |
3.1 ± 0.2 |
6.0 ± 0.7 |
37 ± 3 |
778 ± 243 |
2335 ± 2402 |
50 ± 9 |
2.2 ± 0.3 |
77.2 ± 5.1 |
39.6 ± 4.6 |
38.1 ± 9.0 |
T6 |
5.8 ± 1.2b |
3.0 ± 0.1 |
6.1 ± 0.4 |
39 ± 9 |
743 ± 240 |
1560 ± 980 |
51 ± 8 |
2.5 ± 0.4 |
75.2 ± 6.4 |
37.5 ± 5.7 |
37.3 ± 11.3 |
T7 | 4.9 ± 0.5b | 3.0 ± 0.1 | 6.4 ± 0.5 | 44 ± 8 | 576 ± 186 | 1072 ± 713 | 60 ± 13 | 2.5 ± 0.7 | 74.6 ± 7.0 | 39.5 ± 5.8 | 34.9 ± 12.1 |
CA, calcium; BUN, blood urea nitrogen; CRE, creatinine; AST, aspartate aminotransferase; GGT, γ-glutamyl transferase; CK, creatine kinase; TBIL, total bilirubin, TP, total protein; ALB, albumin; GLOB, globulin. T0, immediately prior to injection of digoxin; T1-T7, 1, 2, 3, 4, 24, 48 and 72 h after digoxin administration. bDiffer significantly at P < 0.05 compared to pre-injection values.