Table 3.
Subgroup of ischaemic strokes or TIA stratified by age groups (demographic characteristics, risk factors, and stroke subtypes)
| |
Total groups |
|
Age 18-34 years |
|
Age 35-44 years |
|
Age 45-55 years |
|
|---|---|---|---|---|---|---|---|---|
| sifap1(n = 4467) | GQH(n = 14522) | sifap1(n = 563)12.6% | GQH(n = 1049)7.2%*** | sifap1(n = 1224)27.4% | GQH(n = 2962)20.4%*** | sifap1(n = 2680)60% | GQH(n = 10511)72.4%*** | |
| Sex (males); (n = 4467, Sifap1) |
59.4% |
61.2%* |
42.8% |
46.3% |
57.9% |
57.9% |
63.5% |
63.5% |
| Age (years); mean, median and 25th-75th percentile (n = 4467, Sifap1) |
44.747 (40-51) |
47.5*** 50 (44-53) |
28.329 (25-32) |
28.4 29 (25-32) |
40.541 (38-43) |
40.6 41 (39-43) |
50.150 (47-53) |
51.4*** 51 (48-53) |
| Previous cerebrovascular event (n = 4466, Sifap1) |
16.9% |
11.9%*** |
12.8% |
7.7%** |
15.4% |
8.2%*** |
18.6% |
13.3%*** |
| Proportion of TIA (n = 4467, Sifap1) |
24.0% |
36.4%*** |
21.8% |
41.5%*** |
25.1% |
39.7%*** |
23.9% |
34.9%*** |
| Vascular risk profile |
|
|
|
|
|
|
|
|
| Hypertension (n = 4439, Sifap1) |
46.6% |
49.5%** |
13.1% |
11.6% |
36.7% |
31.7%** |
58.2% |
58.2% |
| Diabetes mellitus (n = 4443, Sifap1) |
10.3% |
14.4%*** |
2.0% |
3.1% |
7.7% |
8.6% |
13.3% |
17.1%*** |
| Current smoking (n = 4466, Sifap1) |
42.5% |
40.8%* |
37.5% |
33.5% |
42.1% |
41.3% |
43.8% |
41.5% |
| Stroke subtypes according to TOAST |
n = 4345 |
n = 14169 |
n = 555 |
n = 1006 |
n = 1201 |
n = 2902 |
n = 2589 |
n = 10261 |
| Atherosclerosis |
16.4% |
22.3%***a |
4.1% |
8.8%***a |
10.4% |
13.6%***a |
21.8% |
26%***a |
| Cardiac embolic source |
15.1% |
12.1% |
18.6% |
15.3% |
17.7% |
13.4% |
13.2% |
11.4% |
| Small artery occlusion |
13.7% |
19.2% |
6.3% |
8.2% |
9.5% |
13.7% |
17.2% |
21.8% |
| Other determined cause |
16.5% |
9.8% |
24.5% |
16.7% |
20.8% |
14.3% |
12.8% |
7.8% |
| Undetermined cause | 38.3% | 36.7% | 46.5% | 51.0% | 41.6% | 45.0% | 34.9% | 33.0% |
*p < 0.05.
**p < 0.01.
***p < 0.001.
athe test statistic was calculated by using all five TOAST classification categories.