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. 2014 Mar 7;33(1):25. doi: 10.1186/1756-9966-33-25

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Copyright © 2014 Zhuang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of ETK on cell proliferation, apoptosis, migration and invasion of RCC cells 786-O and 769-P. Comparing ETK siRNA group with negative control siRNA group, (A) Cell proliferation was significantly inhibited after ETK siRNA transfection at 48 h. (B) Flow cytometry indicated that cell apoptosis increased after ETK siRNA transfection at 48 h. (C) Cell migration was significantly inhibited after ETK siRNA transfection at 36 h. (D) Transwell matrigel invasion assay showed a significant decrease of invaded cells after ETK siRNA transfection at 48 h. (**, P<0.01).