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. 2014 Mar 26;2014:249856. doi: 10.1155/2014/249856

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Copyright © 2014 Laurent Dortet et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Schematic representation of bla _NDM-associated genetic structures identified among Gram-negative clinical isolates. (a) Structure found in A. baumannii, where the bla _NDM gene is part of the composite transposon Tn125. (b) Structures found in Enterobacteriaceae and P. aeruginosa where ISAba125 is presented as full or truncated element with ble _MBL gene (bleomycin resistance encoding gene) also being present as full or truncated gene. Genes and their corresponding transcription orientations are represented by horizontal arrows. oriIS of ISCR21 is indicated by a circle. The bla _NDM promoter is indicated (P). IS, insertion sequence; gene names are abbreviated according to their corresponding proteins: ble _MBL, bleomycin resistance gene; Δiso for truncated phosphoribosylanthranilate isomerase; Δpac for truncated phospholipid acetyltransferase.