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Downexpression of miR-210 increased apoptosis via HIF-1α in hypoxic C28/I2 cells. Apoptosis of C28/I2 cells transfected with miR-210 mimics, miR-anti, or HIF-1α si was measured by flow cytometry after 48 h upon hypoxia or normoxia. (a) Apoptotic rate in C28/I2 cells on normoxia. (b) Apoptotic rate in hypoxic C28/I2 cells. Three individual experiments were conducted. The significant differences were denoted as *P < 0.05.
