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. Author manuscript; available in PMC: 2014 Apr 13.
Published in final edited form as: Annu Rev Biomed Eng. 2010 Aug 15;12:233–258. doi: 10.1146/annurev-bioeng-070909-105305

Figure 3.

Figure 3

Vm responses to uniform electric field predicted by the classical cable model and the sawtooth model. (a) The cable model predicts that Vm effects are limited to a group of cells in the immediate vicinity of the shocking electrodes. (b) The sawtooth model predicts a pattern of alternating positive and negative Vm changes (shown by Vm1) due to abrupt changes in intracellular resistivity across intercellular junctions. The cable model prediction is shown by Vm0. (c) The summed predicted ΔVm from the cable and sawtooth models (17).