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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Mol Microbiol. 2014 Jan 21;91(5):965–975. doi: 10.1111/mmi.12508

Figure 3.

Figure 3

Locations of AcrA suppressor alterations. A cartoon showing the model of full-length AcrA based on the partial X-ray structure of AcrA (2F1M) and the full-length MexA structure (2V4D). Locations of AcrA substitutions, which compensate for the defect of an AcrB β-hairpin mutant, are shown in red with sticks and transparent space-fill representations. AcrA residue numbering corresponds to that of the mature protein. Positions of the four AcrA domains and those that interact with TolC and AcrB are shown.