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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Mol Microbiol. 2014 Jan 21;91(5):965–975. doi: 10.1111/mmi.12508

Table 1.

Minimal inhibitory concentration values of various AcrB mutants.

AcrAB proteinsa MIC (μg ml-1)b
Erythromycin Novobiocin

AcrA+ AcrB+ >128 >128
AcrA- AcrB- 2 2
AcrA+ AcrB H1Δ252-256 16 8-16
AcrA+ AcrB Poly A H1252-256 64-128 64
AcrA+ AcrB H2Δ793-797 128 64
AcrA+ AcrB Poly A H2793-797 128 64
AcrA+ AcrB Poly A H1252-256, Poly A H2793-797 32 16
a

AcrAB proteins were expressed from pACYC184 in a ΔacrAB background.

b

MIC, minimal inhibitory concentration.