Table 1.
AcrAB proteinsa | MIC (μg ml-1)b
|
|
---|---|---|
Erythromycin | Novobiocin | |
| ||
AcrA+ AcrB+ | >128 | >128 |
AcrA- AcrB- | 2 | 2 |
AcrA+ AcrB H1Δ252-256 | 16 | 8-16 |
AcrA+ AcrB Poly A H1252-256 | 64-128 | 64 |
AcrA+ AcrB H2Δ793-797 | 128 | 64 |
AcrA+ AcrB Poly A H2793-797 | 128 | 64 |
AcrA+ AcrB Poly A H1252-256, Poly A H2793-797 | 32 | 16 |
AcrAB proteins were expressed from pACYC184 in a ΔacrAB background.
MIC, minimal inhibitory concentration.