Table 1.
Genotype positive carrier females are arranged by descending age. All males have good vision except IV:2 who showed RPE loss involving the fovea OS. IV:10 and IV:11 were examined but not genetically tested (NT: not tested).
| Patient | Sex | Age | T1194G | Vision (OD;OS) | Findings |
|---|---|---|---|---|---|
| II:3 | F | 89 | + | 20/400;20/200 | Diffuse scalloped retina/RPE atrophy with pigment clumping |
| III:1 | F | 61 | + | HM;HM | Diffuse scalloped retina/RPE atrophy with pigment clumping |
| III:5 | F | 48 | + | 20/20;20/25 | Moderate macular RPE changes and autofluorescence irregularities |
| III:3 | F | 44 | + | 20/20;20/20 | Moderate macular RPE changes and autofluorescence irregularities |
| IV:8 | F | 30 | + | 20/20;20/20 | Mild macular pigmentary mottling |
| IV:6 | F | 22 | + | 20/20;20/20 | Mild macular pigmentary mottling |
| IV:1 | M | 39 | + | 20/40;20/25 | Peripheral pigment clumping with macular RPE atrophy |
| IV:2 | M | 34 | + | 20/20;20/100 | Peripheral pigment clumping with macular RPE atrophy |
| IV:3 | M | 32 | + | 20/20;20/20 | Peripheral pigment clumping with macular RPE atrophy |
| IV:4 | M | 27 | + | 20/20;20/20 | Peripheral pigment clumping with macular RPE atrophy |
| IV:5 | M | 39 | + | 20/20;20/25 | Peripheral pigment clumping with macular RPE atrophy |
| IV:9 | M | 28 | + | 20/30;20/25 | Peripheral pigment clumping with macular RPE atrophy |
| IV:10 | F | 39 | NT | 20/20;20/20 | Normal exam and autofluorescence |
| IV:11 | M | 31 | NT | 20/40;20/30 | Normal exam and autofluorescence |