Skip to main content
. 2014 May;95(5):809–815. doi: 10.1189/jlb.0913482

Figure 3. Infection of IL-17RB−/− C5BL/6 mice demonstrates a reduction in disease pathology and alteration of cytokine responses.

Figure 3.

(A) Examination of lung pathology, 8 days post-RSV infection, demonstrated a reduction in inflammation and PAS-stained mucus production. (B) Quantitative PCR of RSV G protein in the lungs of 8-day-infected mice. The cytokine mRNA expression in the lungs (C) and protein in RSV-rechallenge draining LN cells (D) displayed a different profile in IL-17RB−/− mice. (E) The mRNA expression of GATA3 and T-bet transcription factors was reduced in IL-17RB−/− mice. Data represent mean ± se from five mice/group and are representative of three repeat studies. *P < 0.05.