Table 1.
Relationship of serum IL-33 levels with clinicopathological parameters of breast cancer patients.
Variables | IL-33 level (pg/ml) |
|||
---|---|---|---|---|
N | Mean | SD | P value | |
Age | ||||
≤50 years | 30 | 35.87 | 11.00 | 0.481 |
>50 years | 34 | 38.21 | 14.78 | |
Menopausal statusa | ||||
No | 33 | 36.19 | 11.33 | 0.992 |
Yes | 30 | 36.52 | 12.26 | |
Size | ||||
≤2 cm | 26 | 36.50 | 11.52 | 0.760 |
>2 cm | 38 | 37.53 | 14.21 | |
AJCC stage | ||||
I + II | 44 | 37.93 | 12.11 | 0.465 |
III | 20 | 35.32 | 15.23 | |
Histological gradeb | ||||
1 + 2 | 30 | 36.51 | 13.58 | 0.915 |
3 | 23 | 36.14 | 10.64 | |
ER expressionc | ||||
Negative | 26 | 32.79 | 10.84 | 0.033 |
Positive | 37 | 39.92 | 13.97 | |
PR expressionc | ||||
Negative | 32 | 36.76 | 16.28 | 0.896 |
Positive | 31 | 37.20 | 9.17 | |
HER2 expressionc | ||||
No | 46 | 37.82 | 14.28 | 0.409 |
Yes | 17 | 34.71 | 9.48 | |
Ki-67 expressionc | ||||
Low | 15 | 43.74 | 19.40 | 0.021 |
High | 48 | 34.86 | 9.86 | |
Lymph node metastasis | ||||
≤3 | 56 | 37.59 | 13.52 | 0.445 |
>3 | 8 | 33.78 | 9.67 | |
Family history | ||||
No | 58 | 36.00 | 11.69 | 0.034 |
Yes | 6 | 47.81 | 21.29 |
aOne case missing this information because the patient was male.
bTwo cases with invasive lobular carcinomas, one case with an intraductal papillary carcinoma, and in eight cases, only biopsy samples were available without information on histological grade.
cOne case was discharged after biopsy, without information on ER, PR, HER2, and Ki-67 expression.