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. 2014 Apr 7;5:141. doi: 10.3389/fimmu.2014.00141

Table 1.

Relationship of serum IL-33 levels with clinicopathological parameters of breast cancer patients.

Variables IL-33 level (pg/ml)
N Mean SD P value
Age
  ≤50 years 30 35.87 11.00 0.481
  >50 years 34 38.21 14.78
Menopausal statusa
 No 33 36.19 11.33 0.992
 Yes 30 36.52 12.26
Size
  ≤2 cm 26 36.50 11.52 0.760
  >2 cm 38 37.53 14.21
AJCC stage
 I + II 44 37.93 12.11 0.465
 III 20 35.32 15.23
Histological gradeb
 1 + 2 30 36.51 13.58 0.915
 3 23 36.14 10.64
ER expressionc
 Negative 26 32.79 10.84 0.033
 Positive 37 39.92 13.97
PR expressionc
 Negative 32 36.76 16.28 0.896
 Positive 31 37.20 9.17
HER2 expressionc
 No 46 37.82 14.28 0.409
 Yes 17 34.71 9.48
Ki-67 expressionc
 Low 15 43.74 19.40 0.021
 High 48 34.86 9.86
Lymph node metastasis
  ≤3 56 37.59 13.52 0.445
  >3 8 33.78 9.67
Family history
 No 58 36.00 11.69 0.034
 Yes 6 47.81 21.29

aOne case missing this information because the patient was male.

bTwo cases with invasive lobular carcinomas, one case with an intraductal papillary carcinoma, and in eight cases, only biopsy samples were available without information on histological grade.

cOne case was discharged after biopsy, without information on ER, PR, HER2, and Ki-67 expression.