Table 2.

List of proteins of interest (POIs), which were selected for this study.

No	POI group	Description	Interest
1	Alcohol DH	Interconversion of aldehydes/ketones and alcohols	Biocatalytic synthesis of chiral intermediates
2	Formate DH	Conversion of CO2 into format	Biological carbon capture
3	Formaldehyde DH	Interconversion of formaldehyde and formate	Biological carbon capture, methanol conversion
4	Carbon monoxide DH	Interconversion of CO and CO2	Biological carbon capture, metalloenzyme structures
5	Ene reductase	Stereoselective reduction of alkenes	Biocatalytic synthesis of chiral intermediates
6	Protease	Hydrolysis of peptide bonds	Detergents, food, and leather processing
7	Terpene synthase	Synthesis of basic, (mulit-)cyclic terpene structures	Biocatalytic synthesis of complex intermediates
8	Nitrogenase	Fixation of nitrogen from air	metalloenzyme structure and function
9	Lipase	Hydrolysis of triglyceride esters	Detergents, biodiesel synthesis
10	Carbonic anhydrase	Interconversion of CO2 and Bicarbonate	Biological carbon capture, metalloenzyme structures
11	Acetylene hydratase	Synthesis of aldehydes from acetylene	Biocatalytic synthesis intermediates
12	Acetyl-CoA synthetase	Activation of acetate for further conversion	Biological carbon capture metabolism
13	pylRS	Aminoacyl tRNA synthetase, acting on pyrrolysine	Synthetic biology, expanding the genetic code
14	pyltRNA	tRNA coding for pyrrolysine	Synthetic biology, expanding the genetic code
15	Aquaporin	Integral membrane proteins controlling osmotic pressure	Water desalination membranes