Table 1. Pearson correlation and root mean square error values obtained for each pancreatic cell line by their respective QSAR models.
S. No. | Cell Line | ND* | D1 | R | R2 | RMSE | D2 | R | R2 | RMSE |
---|---|---|---|---|---|---|---|---|---|---|
1. | AsPC-1 | 92 | 45 | 0.84 | 0.70 | 1.6 | 23 | 0.81 | 0.66 | 1.78 |
2. | BxPC-3 | 92 | 47 | 0.82 | 0.67 | 1.82 | 19 | 0.82 | 0.67 | 1.83 |
3. | CAPAN-1 | 96 | 42 | 0.83 | 0.69 | 1.61 | 21 | 0.84 | 0.71 | 1.58 |
4. | Capan-2 | 90 | 54 | 0.86 | 0.73 | 1.47 | 22 | 0.82 | 0.67 | 1.63 |
5. | HPAF-II | 95 | 42 | 0.86 | 0.74 | 1.45 | 22 | 0.85 | 0.73 | 1.48 |
6. | HuP-T3 | 96 | 54 | 0.85 | 0.73 | 1.57 | 22 | 0.84 | 0.71 | 1.63 |
7. | HuP-T4 | 92 | 41 | 0.79 | 0.61 | 2.00 | 24 | 0.83 | 0.69 | 1.81 |
8. | KP-4 | 88 | 62 | 0.82 | 0.68 | 1.94 | 22 | 0.82 | 0.67 | 2.04 |
9. | MIA-PaCa-2 | 96 | 45 | 0.85 | 0.71 | 1.81 | 23 | 0.86 | 0.73 | 1.76 |
10. | MZ1-PC | 132 | 136 | 0.79 | 0.61 | 1.94 | 29 | 0.73 | 0.53 | 2.16 |
11. | PANC-03-27 | 91 | 44 | 0.8 | 0.64 | 2.00 | 20 | 0.82 | 0.67 | 1.91 |
12. | PANC-08-13 | 92 | 50 | 0.81 | 0.65 | 1.75 | 22 | 0.82 | 0.68 | 1.74 |
13. | PANC-10-05 | 95 | 41 | 0.81 | 0.65 | 1.92 | 24 | 0.85 | 0.73 | 1.71 |
14. | PSN1 | 129 | 116 | 0.64 | 0.42 | 2.68 | 31 | 0.63 | 0.39 | 2.81 |
15. | SW1990 | 94 | 38 | 0.77 | 0.56 | 1.89 | 23 | 0.80 | 0.63 | 1.83 |
16. | YAPC | 86 | 65 | 0.89 | 0.79 | 1.24 | 21 | 0.86 | 0.74 | 1.45 |
*ND: Number of drugs used to develop QSAR models; D1: Number of descriptors selected from the CfsSubsetEval algorithm; D2: Number of descriptor selected from CfsSubsetEval followed by F-stepping; R: Pearson Correlation; RMSE: Root Mean Square Error.