Figure 2.
20 h early DEP increases post-infection sleep and improves survival during infection with P. aeruginosa. (A, C) Mean ± SEM percent time sleeping per 4 h is plotted relative to time of infection with P. aeruginosa in flies subjected to (A) 16 h early DEP; n = 61 for CTRL and n = 59 for 16 h early DEP (**P < 0.005; *P < 0.05), and (C) 20 h early DEP; n = 117 for CTRL and n = 139 for 20 h early DEP. (**P < 0.0001; *P < 0.005, Student t-test, Bonferroni corrected). (B, D) Kaplan-Meier plots of flies surviving infection with P. aeruginosa after (B) 16 h early DEP (P = 0.06, log rank test); n = 63 for CTRL and n = 61 flies for 16 h DEP, and (D) 20 h early DEP (P = 1.4 × 10-19, log rank test); n = 155 for CTRL and n = 152 flies for 20 h DEP.
