Figure 7.
Dif; Relish double mutants abolish effects of early DEP on sleep and survival during infection. (A) Mean ± SEM percent time sleeping per 4 h is plotted relative to time of infection with S. marcescens in Dif1/Dif2;RelE20 flies; n = 73 for CTRL and n = 74 for 16 h early DEP. **P < 0.0001, Student t-test (Bonferroni corrected). (B, C) Kaplan-Meier plots of Dif1/Dif2;RelE20 flies surviving (B) an infection with S. marcescens (n = 93 for CTRL and n = 94 for 16 h early DEP, P = 0.6, log rank test); and (C) aseptic injury (n = 95 CTRL and n = 90 for 16 h early DEP; P = 0.35, log rank test).