Table 4.

Results of univariate logistic regression of patient and disease characteristics predicting grade ≥ 2 complications within 8 weeks among patients presenting with mRCC who underwent nephrectomy (n = 195)

Patient characteristics				Disease characteristics
	OR	95% CI	P		OR	95% CI	P
Age at surgery	1.03	1.00–1.07	0.035	Diameter of tumour	0.98	0.90–1.07	0.7
Gender, Female	0.73	0.36–1.47	0.4	No. of initial metastases
Race, Caucasian	0.65	0.21–2.04	0.5	1		Reference
BMI	0.94	0.88–1.01	0.078	≥2	1.04	0.52–2.10	0.9
Preoperative eGFRa	1.00	0.98–1.01	0.6	Location of metastases
Type of symptoms				multiple sites		Reference
none		Reference		lung	0.85	0.37–1.93	0.7
local	1.12	0.42–2.96	0.8	bone	0.96	0.38–2.46	0.9
metastatic	1.30	0.51–3.29	0.6	adrenal	1.30	0.34–4.96	0.7
systemic	1.85	0.69–4.97	0.2	brain	1.30	0.22–7.86	0.8
Low serum Hbb	2.12	1.11–4.07	0.024	other	1.04	0.34–3.18	0.9
High CCac	4.84	1.51–15.5	0.008	Clear cell histology	0.81	0.27–2.44	0.7
Low albumin (<4g/dL)	2.05	1.03–4.09	0.042	Positive surgical margins	1.19	0.48–2.93	0.7
High LDHd	1.41	0.25–7.98	0.7	Positive lymph nodes	0.94	0.39–2.28	0.9
High white blood cell count e	1.18	0.50–2.77	0.7	Pathological T-stage (≥T2)	1.25	0.62–2.54	0.5
Performance measures				Treatment characteristics
	OR	95% CI	P		OR	95% CI	P
Charlson index:				Neoadjuvant treatment	1.08	0.32–3.60	0.9
= 6		Reference		Nephrectomy type:
> 6	1.12	0.53–2.36	0.8	partial		Reference
Age-adjusted Charlson score:				radical	1.05	0.36–3.07	0.9
≤8	0.66	0.34–1.28	0.2	Procedure type:
ASA score:				open		Reference
1		Reference		laparoscopic	1.37	0.39–4.74	0.6
2	0.95	0.09–9.54	>0.9	Side of procedure:
3	1.26	0.13–12.8	0.8	right		Reference
missing				left	0.91	0.48–1.71	0.8
Low KPS (<80%)	12.3	3.83–39.5	<0.001	bilateral	1.00	1.00–1.00	>0.9
Modified MSKCC criteria:				Curative metastasectomy	1.04	0.55–1.96	0.9
favourable		Reference
unfavourable	2.93	1.45–5.90	0.003

^aChronic Kidney Disease Epidemiology Collaboration, ml/min per 1.73m²;

^bmale < 13g/dL, female < 11.5 g/dL;

^c> 1.5-times the upper limit of normal;

^d> 10 mg/dL;

^e> 4–11 K/μL; ASA, American Society of Anesthesiologists; BMI, body mass index; eGFR, estimated GFR.