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. Author manuscript; available in PMC: 2014 Apr 14.
Published in final edited form as: NMR Biomed. 2011 May 25;25(1):113–122. doi: 10.1002/nbm.1723

Figure 5.

Figure 5

Histology and immunohistochemistry of AT and H tumors. In AT tumors, necrosis was found even in small tumors, such as the tumor with V = 118 mm3 (A) for, and increased with tumor volume (V = 2207 mm3) (B). Pimonidazole-positive area also increased with tumor volume of AT tumors (D, E). In contrast, in Dunning H tumors no necrosis was observed even in large tumors (V = 1949 mm3) (C) and only minimal pimonidazole activity was found (F).