Skip to main content
. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Dev Dyn. 2013 Sep 6;242(11):1293–1306. doi: 10.1002/dvdy.24025

Figure 1.

Figure 1

Prickle1 C251X homozygotic mice have stunted growth of appendages extending from the axis. A and D: at E18.5, the Prickle1 C251X/C251X mice (D) have shorter snout, shorter limbs and shorter tail compared with wild-type (A). B, C, E and F: the skeleton from wild-type embryos (B-C) and mutant embryos (E-F) is double stained with Alcian blue and Alizarin red. While the total length of the rib cage does not show significant difference, ribs tend to be shorter in the mutant (compare while arrows in B and E). The mutant has shorter tail due to deformed (black arrow in F) and fewer segments (compare C and F). The scale bar is 5 mm in A and D and 1mm in B, C, E and F.