Table 4.
The characteristics metabolites related to CHD patients.
| Metabolites | Chamical shift | t/z value | P value | Upregulation/downregulation |
|---|---|---|---|---|
| Leucine | 0.97 | −3.867 | 0.000 | ↑ |
| N-Acetyl glycoprotein | 2.02 | −2.552 | 0.011 | ↑ |
| α-Glucose | 3.53, 5.23, 3.84 | −3.576/−3.372/−3.116 | 0.000/0.001/0.002 | ↑ |
| β-Glucose | 4.64, 3.72, 3.9 | −3.081/−3.372/−3.491 | 0.002/0.001/0.000 | ↑ |
| β-Hydroxy isobutyric acid | 1.2 | 2.082 | 0.042 | ↓ |
| Phenylalanine | 3.13 | −3.322 | 0.002 | ↑ |
| Acetone | 2.23 | −2.860 | 0.006 | ↑ |
| HDL | 1.26 | −2.296 | 0.022 | ↑ |
| Glutamate | 2.1 | −3.030 | 0.002 | ↑ |
| Glutamine | 2.14, 3.77 | −2.761/−2.603 | 0.008/0.009 | ↑ |
| Methylamine | 2.54 | −2.422 | 0.019 | ↑ |
| Lysine | 1.73 | −2.194 | 0.028 | ↑ |
| Tyrosine | 3.94 | −2.074 | 0.038 | ↑ |
| Ornithine | 3.79 | −2.467 | 0.014 | ↑ |
| Taurine | 3.43 | −3.918 | 0.000 | ↑ |
| Proline | 3.42 | −3.747 | 0.000 | ↑ |
| Lactic acid | 1.33 | −2.842 | 0.004 | ↑ |
| Tryptophan | 3.49 | −3.628 | 0.000 | ↑ |
| Threonine | 1.34 | −2.057 | 0.040 | ↑ |
| Aspartic acid | 2.68 | −2.339 | 0.023 | ↑ |
| Valine | 1.04, 2.28 | −3.783/−2.738 | 0.000/0.008 | ↑ |
| Acetyl glutamic acid | 2.04 | −3.047 | 0.002 | ↑ |
| Isoleucine | 1.01, 1.98, 0.94, 1.26 | −2.851/−2.731/−2.228/−2.330 | 0.006/0.006/0.026/0.020 | ↑ |
| Lipids | 2.22 | −2.262 | 0.024 | ↑ |
| Histidine | 3.25 | −3.047 | 0.002 | ↑ |
Note. Up- or downregulation mean CHD patients group comparing with healthy people group.