TABLE 4.
Associations between BMI and adipose measures at baseline and odds of poor performance after 9 y in Health ABC participants stratified by sex1
| n | No. with gait speed <1 m/s | Model 1 | P | Model 2 | P | Model 3 | P | |
| Men | ||||||||
| BMI | 726 | 314 | 1.30 (1.11, 1.53)2 | 0.001 | 1.31 (1.07, 1.61) | 0.01 | — | — |
| VAT area | 707 | 305 | 1.25 (1.06, 1.48) | 0.008 | 1.20 (0.99, 1.44) | 0.06 | 1.14 (0.92, 1.40) | 0.23 |
| Abdominal SAT area | 699 | 299 | 1.30 (1.11, 1.52) | 0.001 | 1.29 (1.06, 1.57) | 0.01 | 1.29 (0.99, 1.67) | 0.06 |
| Thigh SAT area | 714 | 308 | 1.25 (1.07, 1.47) | 0.004 | 1.26 (1.06, 1.50) | 0.008 | 1.22 (1.00, 1.50) | 0.05 |
| Thigh IMAT area | 714 | 308 | 1.46 (1.20, 1.76) | <0.001 | 1.54 (1.22, 1.93) | <0.001 | 1.54 (1.18, 2.02) | 0.001 |
| VAT density | 706 | 305 | 0.87 (0.72, 1.05) | 0.15 | 0.93 (0.77, 1.14) | 0.50 | 0.99 (0.80, 1.23) | 0.91 |
| Abdominal SAT density | 697 | 299 | 0.95 (0.79, 1.14) | 0.57 | 1.02 (0.84, 1.23) | 0.87 | 1.06 (0.87, 1.30) | 0.55 |
| Thigh SAT density | 714 | 308 | 0.87 (0.74, 1.03) | 0.11 | 0.86 (0.72, 1.03) | 0.10 | 0.88 (0.73, 1.05) | 0.16 |
| Thigh IMAT density | 714 | 308 | 0.78 (0.66, 0.92) | 0.003 | 0.78 (0.65, 0.93) | 0.006 | 0.80 (0.67, 0.97) | 0.02 |
| Women | ||||||||
| BMI | 843 | 467 | 1.71 (1.45, 2.02) | <0.001 | 1.41 (1.13, 1.76) | 0.002 | — | — |
| VAT area | 816 | 451 | 1.47 (1.24, 1.73) | <0.001 | 1.12 (0.93, 1.36) | 0.24 | 0.96 (0.77, 1.20) | 0.74 |
| Abdominal SAT area | 792 | 432 | 1.51 (1.28, 1.77) | <0.001 | 1.31 (1.06, 1.61) | 0.01 | 1.07 (0.81, 1.42) | 0.62 |
| Thigh SAT area | 828 | 456 | 1.46 (1.23, 1.74) | <0.001 | 1.30 (1.04, 1.62) | 0.02 | 1.10 (0.84, 1.44) | 0.49 |
| Thigh IMAT area | 828 | 456 | 1.66 (1.40, 1.97) | <0.001 | 1.36 (1.12, 1.64) | 0.002 | 1.25 (1.01, 1.54) | 0.04 |
| VAT density | 815 | 451 | 0.80 (0.68, 0.95) | 0.01 | 0.93 (0.77, 1.12) | 0.44 | 1.03 (0.84, 1.26) | 0.81 |
| Abdominal SAT density | 789 | 432 | 1.05 (0.89, 1.23) | 0.57 | 1.04 (0.87, 1.24) | 0.71 | 1.08 (0.90, 1.30) | 0.41 |
| Thigh SAT density | 828 | 456 | 1.05 (0.90, 1.22) | 0.55 | 1.00 (0.84, 1.18) | 0.96 | 1.00 (0.84, 1.19) | 0.97 |
| Thigh IMAT density | 828 | 456 | 0.88 (0.76, 1.03) | 0.11 | 0.92 (0.78, 1.09) | 0.35 | 0.96 (0.81, 1.14) | 0.66 |
1
Multivariate logistic regression models were used to assess odds of poor performance for each SD increment in BMI and adipose measure. Model 1 was adjusted for age, race, and study site. Model 2 was adjusted as for model 1 and for education, smoking status, prevalent disease, physical activity, midlife weight, and pain. Model 3 was adjusted as for model 2 and for BMI. Health ABC, Health, Aging, and Body Composition Study; IMAT, intermuscular adipose tissue; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.
2
OR; 95% CI in parentheses (all such values).