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. 2014 Winter;13(1):135–141.

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© 2014 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cytotoxicity effects of the cycloartanes (1-4) in Euphorbia macrostegia on two cancer cell lines MDA-MB48 and MCF-7 . In this panel the cytotoxicity tests were presented on two different cancer cell lines including MDA-MB48 and MCF-7 in the presence of different concentrations (0.1, 1, 10, 50, 100 and 200 μg/mL) of cycloart-25-ene-3β,24-diol (1), cycloart-23(Z)-ene-3β,25-diol (2), cycloart-23(E)-ene-3β, 25-diol (3), and 24-methylene-cycloart-3β-ol (4), and control cells which were not treated (set to 100%). For statistical significance one-way ANOVA was used to analyze the differences between each sample and control (*P < 0.05, **P < 0.01).