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. Author manuscript; available in PMC: 2014 Dec 24.
Published in final edited form as: J Am Coll Cardiol. 2013 Sep 4;62(25):2395–2403. doi: 10.1016/j.jacc.2013.08.715

Figure 5. Relationship between ventricular myofiber work and LV systolic function during pacing.

Figure 5

Total ventricular myofiber work (left), LV myofiber work (middle), and RV myofiber work (right) per cardiac cycle versus LVdP/dtmax in 25 LVP simulations (circles) and 25 BiVP simulations (squares). The left panel indicates that total ventricular myofiber work increased linearly with LVdP/dtmax and that this linear relationship was virtually independent of the pacing mode. The middle and right panel show that LVP and BiVP behaved differently when considering LV and RV myofiber work separately. For both pacing modes, five clusters of simulations can be discriminated by their color, indicating total ventricular activation time (ATTOT) that ranged from 54 to 162 ms for LVP and from 24 to 72 ms for BiVP. Each cluster (e.g. dashed circle) consists of five simulations with the same ATTOT, but with different AV delays (60/80/100/120/140 ms).