Table 1.
Electrical and hemodynamic data from dogs with chronic HF and LBBB (n=6) during baseline (BL), left ventricular pacing (LVP), and biventricular pacing (BiVP).
| p-values |
|||||||
|---|---|---|---|---|---|---|---|
| BL | LVP | BiVP | ANO VA |
BL vs LVP |
BL vs BiVP |
LVP vs BiVP |
|
| QRS duration (ms) | 122±10 | 132±26 | 115±15 | 0.098 | - | - | - |
| heart rate (bpm) | 134±11 | 133±10 | 133±10 | 0.368 | - | - | - |
| ATTOT (ms) | 95±16 | 106±22 | 84±13 | 0.008 | 0.160 | 0.002 | 0.022 |
| ATLV (ms) | 95±16 | 96±14 | 83±13 | <0.001 | 0.701 | 0.001 | 0.003 |
| LV stroke volume (mL) | 15±5 | 17±11 | 18±7 | 0.428 | - | - | - |
| LV pump stroke work (mL*mmHg) | 1022±503 | 1245±883 | 1230±499 | 0.256 | - | - | - |
| LV peak systolic pressure (mmHg) | 77±11 | 79±10 | 79±10 | 0.105 | - | - | - |
| LVdP/dtmax (mmHg/s) | 853±99 | 1023±158 | 1005±127 | 0.034 | 0.038 | 0.035 | 0.295 |
| LV end-diastolic pressure (mmHg) | 20±13 | 19±14 | 21±15 | 0.279 | - | - | - |
| LV end-diastolic volume (mL) | 128±37 | 124±36 | 127±35 | 0.223 | - | - | - |
| RV peak systolic | 32±12 | 29±11 | 31±11 | 0.015 | 0.026 | 0.155 | 0.053 |
| pressure (mmHg) RVdP/dtmax (mmHg/s) | 442±140 | 411±146 | 463±118 | 0.050 | 0.136 | 0.290 | 0.043 |
| RV end-diastolic pressure (mmHg) | 8±6 | 8±4 | 9±7 | 0.894 | - | - | - |
ATLV = LV electrical activation time (including septum and LV free wall); ATTOT = total ventricular electrical activation time (including septum, LV free wall, and RV free wall).