Table 3.
Results of DFS analysis by Cox Proportional Hazards model in no metastasis at diagnosis group (n = 32) for IHH in combination with size.
| Prognostic factor | Univariate | Multivariate* | ||||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |||
| IHH/size | ||||||||
| IHH+/≤9 cm versus IHH−/≤9 cm | 12.78 | 1.36 | 1694.88 | 0.1128* | 6.31 | 0.47 | 934.10 | 0.2831 |
| IHH+/>9 cm versus IHH−/≤9 cm | 17.10 | 1.91 | 2253.96 | 0.0754* | 52.30 | 3.27 | 10906.34 | 0.0378 |
| IHH−/>9 cm versus IHH−/≤9 cm | 20.48 | 2.14 | 2727.27 | 0.0611* | 17.62 | 1.48 | 2614.55 | 0.0907 |
| Necrosis | ||||||||
| >90% versus ≤90% | 0.71 | 0.21 | 2.35 | 0.5716 | 0.62 | 0.16 | 2.39 | 0.5027 |
| Gender | ||||||||
| Male versus female | 1.39 | 0.44 | 4.36 | 0.5795 | 0.33 | 0.03 | 2.10 | 0.2700 |
| Age (years) | 1.02 | 0.99 | 1.05 | 0.1676 | 1.03 | 0.99 | 1.07 | 0.2034 |
*Firth correction to handle small sample sizes.
IHH+: high IHH levels.
IHH−: low IHH levels.