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. Author manuscript; available in PMC: 2015 Feb 11.
Published in final edited form as: Curr Opin Struct Biol. 2014 Feb 11;0:132–140. doi: 10.1016/j.sbi.2014.01.011

Figure 1. Exosome function in the eukaryotic cell.

Figure 1

A) Budding yeast. Nuclear and cytoplasmic forms of the exosome have been detected that use the exosome core (Exo9). Co-factors and co-factor complexes that are either functionally or directly associated with the S. cerevisiae exosome are depicted in either the cytoplasm (Exo10) or nucleus (Exo11). B) Human. Evidence for three different forms of the exosome existed: cytoplasmic, nuclear, and nucleolar. Each associates with different classes of co-factors. Figure prepared by Abigail C. Wasmuth.