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. Author manuscript; available in PMC: 2014 Apr 14.
Published in final edited form as: Cancer Prev Res (Phila). 2008 May 18;1(3):167–173. doi: 10.1158/1940-6207.CAPR-08-0078

Table 3.

Correlations of biopsy features with PSA value, placebo group only

Nonparametric Pearson's Correlation*
Variable Correlation p-value
Gleason score 0.28 < 0.001
Number of cores positive 0.25 < 0.001
Percent of cores positive 0.26 < 0.001
Greatest linear extent of tumor 0.28 < 0.001
Aggregate linear extent of tumor 0.29 < 0.001
Bilateral 0.16 < 0.001
Perineural invasion 0.15 < 0.001
Prostate volume 0.31 < 0.001
Insignificant tumor (Criteria 1)1 −0.32 <0.001
Insignificant tumor (Criteria 2)2 −0.34 <0.001
*

Ranks assigned to PSA values and all linear values; ties broken arbitrarily. Pearson product-moment correlations were calculated on the ranked variables. True dichotomous variables (Bilateral, Perineural invasion, and Insignificant tumor (both criteria)) were not ranked; their correlations were calculated with ranked PSA values.

1

Stage T1c + PSA density < 0.15 ng/ml/cc + Gleason score ≤6 (no pattern 4 or 5) + tumor limited to < 3 cores + no core with greater than 50% involvement.

2

Stage T1c + PSA density < 0.15 ng/ml/cc + Gleason score ≤(no pattern 4 or 5) + tumor limited to < 3 mm on 1 core.