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. Author manuscript; available in PMC: 2014 Apr 14.
Published in final edited form as: Biochim Biophys Acta. 2012 Jun 15;1817(11):2049–2059. doi: 10.1016/j.bbabio.2012.06.004

Fig. 1.

Fig. 1

Time course of changes in superoxide (O2•−) and peroxynitrite (ONOO−) levels during IR. A: The fluorescence probe DHE, via its stable (ethidium) or unstable and labile 2-hydoxyethidium (2-OH-E+) product was used to assess intracellular O2•− emission online in isolated hearts at the LV free wall. B: Dityrosine (DiTyr) fluorescence formed from L-tyrosine in the presence of ONOO− was used to monitor ONOO− online similar to that described for the DHE fluorescence probe. TC: Time control; IR10: 30 min ischemia and 10 min reperfusion; N=4–5 hearts/group/probe; Values are mean ± SEM. *: p < 0.05 vs. TC. See Table 1 for functional data.