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. Author manuscript; available in PMC: 2014 Apr 14.
Published in final edited form as: Biochim Biophys Acta. 2012 Jun 15;1817(11):2049–2059. doi: 10.1016/j.bbabio.2012.06.004

Fig. 7.

Fig. 7

Effects of ONOO− on recombinant (r) VDAC channel activity. A: Characteristic voltage-dependence of rVDAC in response to a ramp voltage protocol from −80 to +80 mV under control conditions. B: Effects of adding ONOO− on rVDAC activity. Current traces show in control and after adding 50 µmol/L ONOO− obtained at a membrane potential of −10 mV. In control, primary conductance was 1.8 nS. Application of ONOO− triggered enhanced opening of VDAC as evidenced by the multiple conductance states. Corresponding all-points amplitude histograms are also shown.