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. Author manuscript; available in PMC: 2014 Apr 14.
Published in final edited form as: Biochim Biophys Acta. 2012 Jun 15;1817(11):2049–2059. doi: 10.1016/j.bbabio.2012.06.004

Table 1.

Cardiac function in IR10, 60, resveratrol and L-NAME treated IR10 groups during baseline, ischemia 30 min and reperfusion 10 and 60 min.

Variable Pre-ischemia Ischemia
30 min		 Reperfusion
10 min		 Reperfusion
60 min
dLVP/dtmax (mm Hg/s)
IR10, 60 2440 ± 119 23 ± 1 1450 ± 172 1550 ± 151
IR10 + RES 2429 ± 104 25 ± 1 1913 ± 119*
IR10 + L-NAME 2778 ± 191 23 ± 1 1799 ± 119*
dLVP/dtmin (mm Hg/s)
IR10, 60 −2178 ± 128 −32 ± 2 −1151 ± 162 −1255 ± 140
IR10 + RES −2140 ± 83 −29 ± 1 −1944 ± 190*
IR10 + L-NAME −2290 ± 134 −29 ± 1 −1722 ± 83*
Sys-dia LVP (mm Hg)
IR10, 60 88 ± 4 0.1 ± 0 38 ± 5 39 ± 4
IR10 + RES 90 ± 4 0.1 ± 0 57 ± 7*
IR10 + L-NAME 95 ± 5 0.1 ± 0 64 ± 4*
Diastolic LVP (mm Hg)
IR10, 60 0 ± 0 10 ± 3 17 ± 3 16 ± 3
IR10 + RES 0 ± 0 1 ± 1* 3 ± 2*
IR10 + L-NAME 0 ± 0 3 ± 2* 4 ± 2*
Coronary flow (ml/min)
IR10, 60 21.2 ± 2.2 0 ± 0 18.6 ± 2.4 19.3 ± 2.2
IR10 + RES 21.6 ± 1.8 0 ± 0 19.4 ± 1.4
IR10 + L-NAME 16.3 ± 2.2* 0 ± 0 15.4 ± 1.6*
Heart rate (beats/min)
IR 10, 60 215 ± 5 0 ± 0 212 ± 6 213 ± 4
IR10 + RES 210 ± 3 0 ± 0 214 ± 7
IR10 + L-NAME 215 ± 4 0 ± 0 220 ± 4

IR10: 30 min of ischemia and 10 min of reperfusion; IR60 only in non-treated group; sys–dia LVP, systolic–diastolic left ventricular pressure; dLVP/dtmax, index of contractility; dLVP/dtmin: index of relaxation; N = 8–10 hearts/group. Values are mean ± SEM.

*

p < 0.05: IR10 + RES, IR10 + L-NAME vs. IR10, 60.